Detalhe da pesquisa
1.
Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation.
Nat Mater
; 20(2): 260-271, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33230326
2.
Characterization of JNJ-2482272 [4-(4-Methyl-2-(4-(Trifluoromethyl)Phenyl)Thiazole-5-yl) Pyrimidine-2-Amine] As a Strong Aryl Hydrocarbon Receptor Activator in Rat and Human.
Drug Metab Dispos
; 50(8): 1064-1076, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35680134
3.
Prediction of renal transporter mediated drug-drug interactions for pemetrexed using physiologically based pharmacokinetic modeling.
Drug Metab Dispos
; 43(3): 325-34, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25504564
4.
Clinical CYP3A inhibitor alternatives to ketoconazole, clarithromycin and itraconazole, are not transported into the liver by hepatic organic anion transporting polypeptides and organic cation transporter 1.
Drug Metab Dispos
; 42(11): 1780-4, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25106415
5.
Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.
Drug Metab Dispos
; 42(1): 182-92, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24194513
6.
Metformin sinusoidal efflux from the liver is consistent with negligible biliary excretion and absence of enterohepatic cycling.
Drug Metab Dispos
; 41(11): 1967-71, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24009308
7.
Ablation of both organic cation transporter (OCT)1 and OCT2 alters metformin pharmacokinetics but has no effect on tissue drug exposure and pharmacodynamics.
Drug Metab Dispos
; 40(6): 1170-7, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22407892
8.
Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats using loperamide, paclitaxel, sulfasalazine, and carboxydichlorofluorescein pharmacokinetics.
Drug Metab Dispos
; 40(9): 1825-33, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22711747
9.
Prediction of Transporter-Mediated Drug-Drug Interactions for Baricitinib.
Clin Transl Sci
; 10(6): 509-519, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28749581
10.
3D Proximal Tubule Tissues Recapitulate Key Aspects of Renal Physiology to Enable Nephrotoxicity Testing.
Front Physiol
; 8: 123, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28337147
11.
Rhodamine inhibitors of P-glycoprotein: an amide/thioamide "switch" for ATPase activity.
J Med Chem
; 52(10): 3328-41, 2009 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19402665